> For the complete documentation index, see [llms.txt](https://kobic.gitbook.io/kvar/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://kobic.gitbook.io/kvar/1.-overview.md). # 1. Overview ## 1. About KVar KVar (Korean Variant Archive) is a repository that collects, stores, and manages genomic variant data across a wide taxonomic range, including *Homo sapiens* and other organisms. KVar accommodates two major variant classes: * **Single nucleotide polymorphisms (SNPs)** — collectively referring to small variants such as single-nucleotide variations and short insertions/deletions (indels) up to 50 base pairs (bp) in length. * **Structural variants (SVs)** — large-scale genomic variations greater than 50 bp, including deletions (DEL), duplications (DUP), insertions (INS), inversions (INV), translocations (BND), and copy number variants (CNV). KVar functions as a component of the **Korean BioData Station (K-BDS)**, ensuring national-scale variant data archiving and interoperability with international repositories (e.g., dbSNP, dbVar, EVA) through standardized metadata and accession systems.\ KVar exclusively accepts variant data generated by **sequencing-based detection methods**, such as next-generation sequencing (NGS) or long-read sequencing platforms, while data derived from **hybridization-based technologies** (e.g., microarrays or targeted capture assays) are not supported. ## 2. Key features of KVar * **Integrated SNP and SV management**\ KVar collects and manages both SNP and SV data within a single repository, each with separate accession systems. * **Support for non-human species**\ Variant data from *Homo sapiens* and various non-human organisms are accepted and curated. * **Study-based summary statistics**\ Variant information is organized by study (cohort) and includes allele frequency, position, and variant type. * **Genome browser visualization**\ Users can explore where each variant is located within the genome through an interactive browser.
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