KEA metadata guide

Introduction

KEA metadata provides standardized information for describing functional genomics studies, encompassing overall study design, protocols for sample collection and data processing, and technical details of experimental factors. The metadata framework ensures that each dataset is described in a consistent and reproducible manner, facilitating data sharing and reuse.

Metadata structure

KEA metadata is organized into five major parts, each describing a different level of information in the experimental workflow.

Part
Section Title
Description

Part 1

Submission Type

Defines the submission category (HTS or Microarray), data type, completeness, and release date.

Part 2

Study Information

Describes the overall study — including title, abstract, contributors, experimental type, and design.

Part 3

Protocols

Provides detailed descriptions of experimental protocols used for sample preparation and data processing.

Part 4

Sample & Experimental Details

Captures experimental metadata, including molecule type and other experimental factors.

Part 5

Result Files

Lists and categorizes all uploaded data files

Metadata by submission type

KEA supports two major types of functional genomics experiments, each with tailored metadata fields:

1. High-throughput sequencing (HTS)

Key metadata fields:

  • Library name and Sample details

  • Material type (e.g., polyA RNA, genomic DNA)

  • Factor value (e.g., Disease, Cell type, Compound, Time)

  • Description

  • Platform ID (e.g., GPL6805, GPL30172)

2. Microarray

Key metadata fields:

  • Detailed sample title

  • Source name

  • Molecule (e.g., polyA RNA, genomic DNA)

  • Label (e.g., biotin, Cy3 and Cy5)

  • Description

  • Platform ID (e.g., GPL6805, GPL30172)

  • Factor value (e.g., Disease, Cell type, Compound, Time)

Standard registration form

For more detailed information, please refer to the following document:

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